Clinical Spectrum of Primaquine-induced Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficiency: A 9-Year Hospitalization-based Study From the Brazilian Amazon.
Clin Infect Dis
; 69(8): 1440-1442, 2019 09 27.
Article
en En
| MEDLINE
| ID: mdl-30753364
ABSTRACT
Despite glucose-6-phosphate dehydrogenase (G6PD) deficiency prevalence of 5% in the Amazon, primaquine is administered without G6PD screening. This is an important cause of hospitalization among Plasmodium vivax-infected individuals, leading to life-threatening anemia and acute renal failure across endemic areas. In Manaus, the frequency of primaquine-induced hemolysis was 85.2 cases per 100 000 primaquine users.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Plasmodium vivax
/
Primaquina
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Malaria Vivax
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Insuficiencia Renal
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Deficiencia de Glucosafosfato Deshidrogenasa
/
Antimaláricos
Tipo de estudio:
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
País como asunto:
America do sul
/
Brasil
Idioma:
En
Año:
2019
Tipo del documento:
Article