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Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi, Jonas Samuel; Basu, Titiksha; Pellmann, Maximilian; Kaiser, Sandra; Steinemann, Doris; Sanders, Mathijs A; Hinai, Adil S A; Zeilemaker, Annelieke; Bojtine Kovacs, Sarolta; Koellerer, Christoph; Ostendorp, Jenny; Aumann, Konrad; Wang, Wei; Raffoux, Emmanuel; Cassinat, Bruno; Bullinger, Lars; Schlegelberger, Brigitte; Valk, Peter J M; Pahl, Heike Luise.
  • Jutzi JS; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Basu T; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Pellmann M; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Kaiser S; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Steinemann D; Department of Human Genetics, Hannover Medical School, Hannover, Germany.
  • Sanders MA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Hinai ASA; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Zeilemaker A; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
  • Bojtine Kovacs S; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Koellerer C; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Ostendorp J; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Aumann K; Institute for Surgical Pathology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Wang W; Section of Molecular Hematology, Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
  • Raffoux E; Hôpital Saint-Louis, Paris 7 University, Service d'Hématologie Adulte, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.
  • Cassinat B; APHP, Hôpital Saint-Louis, Laboratoire de Biologie Cellulaire, Paris, France.
  • Bullinger L; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany; and.
  • Schlegelberger B; Department of Hematology, Oncology and Tumor Immunology, Charité-University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany.
  • Valk PJM; Department of Human Genetics, Hannover Medical School, Hannover, Germany.
  • Pahl HL; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
Blood ; 133(16): 1766-1777, 2019 04 18.
Article en En | MEDLINE | ID: mdl-30755419
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Transformación Celular Neoplásica / Sarcoma Mieloide / Subunidad p45 del Factor de Transcripción NF-E2 Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Transformación Celular Neoplásica / Sarcoma Mieloide / Subunidad p45 del Factor de Transcripción NF-E2 Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article