Systematic Review: Distribution of Age and Intervention Modalities in Therapeutic Clinical Trials for Autism Spectrum Disorder.
J Autism Dev Disord
; 50(6): 2208-2216, 2020 Jun.
Article
en En
| MEDLINE
| ID: mdl-30815774
ABSTRACT
The prevalence of ASD remains relatively stable across the lifespan, necessitating a quantitative understanding of how intervention clinical research is applied across age groups. Here we report a systematic review of treatment studies between 2013 and 2017, enrolling 11,213 subjects with ASD in 218 studies. Individuals under 18 years old constituted the majority of studies (84%) and subjects (92%). Subjects under 18 years old were more likely to be enrolled in behavioral studies (OR (CI) = 1.34 (1.17-1.54)), and less likely to be enrolled in pharmacological (OR = 0.60 (0.52-0.69)) studies than subjects ≥ 18 years old. Identified disparities in both intervention modalities and outcome measures should serve to guide future research priorities.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ensayos Clínicos como Asunto
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Distribución por Edad
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Trastorno del Espectro Autista
Tipo de estudio:
Prevalence_studies
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Risk_factors_studies
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Systematic_reviews
Límite:
Adolescent
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Child
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Female
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Humans
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Male
Idioma:
En
Año:
2020
Tipo del documento:
Article