Duration of immunity for an inactivated Mycoplasma hyorhinis vaccine in pigs.
Vet Microbiol
; 230: 273-277, 2019 Mar.
Article
en En
| MEDLINE
| ID: mdl-30827400
ABSTRACT
Mycoplasma hyorhinis (Mhr) is a pathogen of pigs causing polyserositis and polyarthritis. The most susceptible population are nursery pigs of approximately 7 weeks of age, although we have shown that clinical signs can persist into finishing aged animals after a late-nursery infection. We have previously demonstrated the efficacy of a novel inactivated Mhr vaccine for the reduction of lameness and polyserositis in caesarian-derived colostrum-deprived (CDCD) pigs vaccinated at 3 weeks and challenged with Mhr at 6 weeks of age. Here we evaluated the duration of immunity (DOI) of the same vaccine. Vaccine or placebo was administered to CDCD pigs at 3 weeks of age. Pigs were challenged with Mhr at either 10 weeks of age (=7 week DOI) or 13 weeks of age (=10 week DOI). In the 7 week DOI, vaccination provided significant reductions in lameness (p = 0.0018), arthritis (p = 0.0002), and pericarditis (p = 0.0312) versus the placebo control. In the 10 week DOI, a significant reduction in arthritis (p = 0.0320) was observed in the vaccine group as compared to the placebo group. Both vaccine groups showed a significant increase (p < 0.0001) in the post-challenge average daily gain (ADG), gaining 0.2 kg/day more than their respective placebo groups.
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Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Pericarditis
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Artritis
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Enfermedades de los Porcinos
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Vacunas Bacterianas
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Mycoplasma hyorhinis
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Infecciones por Mycoplasma
Límite:
Animals
Idioma:
En
Año:
2019
Tipo del documento:
Article