NIK-IKK complex interaction controls NF-&#954;B-dependent inflammatory activation of endothelium in response to LTßR ligation.

Kucharzewska, Paulina; Maracle, Chrissta X; Jeucken, Kim C M; van Hamburg, Jan Piet; Israelsson, Elisabeth; Furber, Mark; Tas, Sander W; Olsson, Henric K

NIK-IKK complex interaction controls NF-κB-dependent inflammatory activation of endothelium in response to LTßR ligation.

Kucharzewska, Paulina; Maracle, Chrissta X; Jeucken, Kim C M; van Hamburg, Jan Piet; Israelsson, Elisabeth; Furber, Mark; Tas, Sander W; Olsson, Henric K.

Kucharzewska P; Respiratory, Inflammation and Autoimmunity IMED Biotech Unit, AstraZeneca, Gothenburg, SE-431 83 Mölndal, Sweden paulina_kucharzewska_siembieda@sggw.pl.
Maracle CX; Amsterdam Rheumatology and Immunology Center, Department of Clinical Immunology and Rheumatology and Laboratory for Experimental Immunology, Academic Medical Center/University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Jeucken KCM; Amsterdam Rheumatology and Immunology Center, Department of Clinical Immunology and Rheumatology and Laboratory for Experimental Immunology, Academic Medical Center/University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
van Hamburg JP; Amsterdam Rheumatology and Immunology Center, Department of Clinical Immunology and Rheumatology and Laboratory for Experimental Immunology, Academic Medical Center/University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Israelsson E; Respiratory, Inflammation and Autoimmunity IMED Biotech Unit, AstraZeneca, Gothenburg, SE-431 83 Mölndal, Sweden.
Furber M; Respiratory, Inflammation and Autoimmunity IMED Biotech Unit, AstraZeneca, Gothenburg, SE-431 83 Mölndal, Sweden.
Tas SW; Amsterdam Rheumatology and Immunology Center, Department of Clinical Immunology and Rheumatology and Laboratory for Experimental Immunology, Academic Medical Center/University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Olsson HK; Respiratory, Inflammation and Autoimmunity IMED Biotech Unit, AstraZeneca, Gothenburg, SE-431 83 Mölndal, Sweden.

J Cell Sci ; 132(7)2019 04 03.

Article en En | MEDLINE | ID: mdl-30837284

Asunto(s)

Células Endoteliales/metabolismo; Receptor beta de Linfotoxina/metabolismo; FN-kappa B/metabolismo; Proteínas Serina-Treonina Quinasas/metabolismo; Transducción de Señal; Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico; Línea Celular; Células Cultivadas; Endotelio/metabolismo; Regulación de la Expresión Génica; Humanos; FN-kappa B/genética; Neovascularización Patológica/metabolismo; Proteínas Serina-Treonina Quinasas/genética; Quinasa de Factor Nuclear kappa B

Palabras clave

Endothelial cells; Inflammation; LTßR; Lymphotoxin-ß receptor; NF-κB-inducing kinase; NIK

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / FN-kappa B / Proteínas Serina-Treonina Quinasas / Células Endoteliales / Receptor beta de Linfotoxina Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article

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