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Memantine selectively prevented the induction of dynamic allodynia by blocking Kir2.1 channel and inhibiting the activation of microglia in spinal dorsal horn of mice in spared nerve injury model.
Chen, Yangyang; Shi, Yiqian; Wang, Guoxiang; Li, Yimei; Cheng, Longzhen; Wang, Yun.
  • Chen Y; 1 Neurology Department, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Shi Y; 1 Neurology Department, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Wang G; 1 Neurology Department, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Li Y; 1 Neurology Department, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Cheng L; 1 Neurology Department, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Wang Y; 1 Neurology Department, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.
Mol Pain ; 15: 1744806919838947, 2019.
Article en En | MEDLINE | ID: mdl-30845882
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Memantina / Microglía / Canales de Potasio de Rectificación Interna / Asta Dorsal de la Médula Espinal / Hiperalgesia Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Memantina / Microglía / Canales de Potasio de Rectificación Interna / Asta Dorsal de la Médula Espinal / Hiperalgesia Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article