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Effective syntheses of 2',4'-BNANC monomers bearing adenine, guanine, thymine, and 5-methylcytosine, and the properties of oligonucleotides fully modified with 2',4'-BNANC.
Fujisaka, Aki; Hari, Yoshiyuki; Takuma, Hiroko; Rahman, S M Abdur; Yoshikawa, Haruhisa; Pang, Juanjuan; Imanishi, Takeshi; Obika, Satoshi.
  • Fujisaka A; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; Faculty of Pharmacy, Osaka Ohtani University, Nishikiori-Kita 3-11-1, Tondabayashi, Osaka 584-8540, Japan.
  • Hari Y; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Nishihama, Yamashiro-cho, Tokushima 770-8514, Japan.
  • Takuma H; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Rahman SMA; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; Department of Clinical Pharmacy & Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
  • Yoshikawa H; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; BNA Inc, 7-7-20 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.
  • Pang J; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Imanishi T; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan; BNA Inc, 7-7-20 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.
  • Obika S; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: obika@phs.osaka-u.ac.jp.
Bioorg Med Chem ; 27(8): 1728-1741, 2019 04 15.
Article en En | MEDLINE | ID: mdl-30862430
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oligonucleótidos / Hidrocarburos Aromáticos con Puentes / Adenina / 5-Metilcitosina / Guanina / Nucleótidos Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Oligonucleótidos / Hidrocarburos Aromáticos con Puentes / Adenina / 5-Metilcitosina / Guanina / Nucleótidos Idioma: En Año: 2019 Tipo del documento: Article