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Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis.
Graham, W Vallen; He, Weiqi; Marchiando, Amanda M; Zha, Juanmin; Singh, Gurminder; Li, Hua-Shan; Biswas, Amlan; Ong, Ma Lora Drizella M; Jiang, Zhi-Hui; Choi, Wangsun; Zuccola, Harmon; Wang, Yitang; Griffith, James; Wu, Jingshing; Rosenberg, Harry J; Wang, Yingmin; Snapper, Scott B; Ostrov, David; Meredith, Stephen C; Miller, Lawrence W; Turner, Jerrold R.
  • Graham WV; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • He W; Laboratory of Chemical Biology & Signal Transduction, The Rockefeller University, New York, NY, USA.
  • Marchiando AM; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Zha J; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda Genomic Resource Center, Soochow University, and Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Singh G; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Li HS; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Biswas A; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda Genomic Resource Center, Soochow University, and Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Ong MLDM; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Jiang ZH; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Choi W; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda Genomic Resource Center, Soochow University, and Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Zuccola H; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
  • Wang Y; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Griffith J; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Suda Genomic Resource Center, Soochow University, and Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China.
  • Wu J; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Rosenberg HJ; Vertex Pharmaceuticals, Boston, MA, USA.
  • Wang Y; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Snapper SB; Vertex Pharmaceuticals, Boston, MA, USA.
  • Ostrov D; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Meredith SC; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Miller LW; Department of Pathology, University of Chicago, Chicago, IL, USA.
  • Turner JR; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Nat Med ; 25(4): 690-700, 2019 04.
Article en En | MEDLINE | ID: mdl-30936544
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinasa de Cadena Ligera de Miosina / Espacio Intracelular / Homeostasis / Mucosa Intestinal Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinasa de Cadena Ligera de Miosina / Espacio Intracelular / Homeostasis / Mucosa Intestinal Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2019 Tipo del documento: Article