miR-140-5p induces cell apoptosis and decreases Warburg effect in chronic myeloid leukemia by targeting SIX1.

Nie, Zi-Yuan; Liu, Xiao-Jun; Zhan, Ying; Liu, Meng-Han; Zhang, Xiao-Yan; Li, Zi-Ye; Lu, Ya-Qiong; Luo, Jian-Min; Yang, Lin

Nie, Zi-Yuan; Liu, Xiao-Jun; Zhan, Ying; Liu, Meng-Han; Zhang, Xiao-Yan; Li, Zi-Ye; Lu, Ya-Qiong; Luo, Jian-Min; Yang, Lin.

Nie ZY; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.
Liu XJ; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.
Zhan Y; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.
Liu MH; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.
Zhang XY; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.
Li ZY; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.
Lu YQ; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.
Luo JM; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China luojianmin1960@126.com.
Yang L; Department of Hematology, The Second Hospital of Hebei Medical University, 215 Heping W Rd, Shijiazhuang 050000, China.

Biosci Rep ; 39(4)2019 04 30.

Article en En | MEDLINE | ID: mdl-30962263

Asunto(s)

Proteínas de Homeodominio/genética; Leucemia Mielógena Crónica BCR-ABL Positiva/genética; Leucemia Mielógena Crónica BCR-ABL Positiva/patología; MicroARNs/genética; Adulto; Anciano; Apoptosis/genética; Proteínas Portadoras/genética; Proteínas Portadoras/metabolismo; Línea Celular Tumoral; Femenino; Regulación Leucémica de la Expresión Génica; Humanos; Células K562; Leucocitos Mononucleares/patología; Leucocitos Mononucleares/fisiología; Masculino; Proteínas de la Membrana/genética; Proteínas de la Membrana/metabolismo; MicroARNs/metabolismo; Persona de Mediana Edad; Hormonas Tiroideas/genética; Hormonas Tiroideas/metabolismo; Proteínas de Unión a Hormona Tiroide

Palabras clave

Chronic myeloid leukemia; PKM2; SIX1; Warburg effect; apoptosis; miR-140-5p

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mielógena Crónica BCR-ABL Positiva / Proteínas de Homeodominio / MicroARNs Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article

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