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Photoluminescence Enhancement of Poly(3-methylthiophene) Nanowires upon Length Variable DNA Hybridization.
Huang, Jingyuan; Choi, Jinho; Lee, Gil Sun; Chen, Fengchun; Cui, Chunzhi; Jin, Long Yi; Park, Dong Hyuk.
  • Huang J; Department of Chemistry, College of Science, and Key Laboratory for Organism Resources of the Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University, Yanji 133002, China. 2154014461@ybu.edu.cn.
  • Choi J; Department of Applied Organic Materials Engineering, Inha University, Incheon 402-751, Korea. jinho@inha.edu.
  • Lee GS; Department of General Education, Kookmin University, Seoul 02707, Korea. gslee@kookmin.ac.kr.
  • Chen F; Department of Chemistry, College of Science, and Key Laboratory for Organism Resources of the Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University, Yanji 133002, China. 2015010396@ybu.edu.cn.
  • Cui C; Department of Chemistry, College of Science, and Key Laboratory for Organism Resources of the Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University, Yanji 133002, China. cuichunzhi@ybu.edu.cn.
  • Jin LY; Department of Chemistry, College of Science, and Key Laboratory for Organism Resources of the Changbai Mountain and Functional Molecules, Ministry of Education, Yanbian University, Yanji 133002, China. lyjin@ybu.edu.cn.
  • Park DH; Department of Applied Organic Materials Engineering, Inha University, Incheon 402-751, Korea. donghyuk@inha.ac.kr.
Polymers (Basel) ; 10(1)2018 Jan 20.
Article en En | MEDLINE | ID: mdl-30966135
ABSTRACT
The use of low-dimensional inorganic or organic nanomaterials has advantages for DNA and protein recognition due to their sensitivity, accuracy, and physical size matching. In this research, poly(3-methylthiophene) (P3MT) nanowires (NWs) are electrochemically prepared with dopant followed by functionalization with probe DNA (pDNA) sequence through electrostatic interaction. Various lengths of pDNA sequences (10-, 20- and 30-mer) are conjugated to the P3MT NWs respectively followed with hybridization with their complementary target DNA (tDNA) sequences. The nanoscale photoluminescence (PL) properties of the P3MT NWs are studied throughout the whole process at solid state. In addition, the correlation between the PL enhancement and the double helix DNA with various lengths is demonstrated.
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