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The Meniscus in Normal and Osteoarthritic Tissues: Facing the Structure Property Challenges and Current Treatment Trends.
Murphy, Caroline A; Garg, Atul K; Silva-Correia, Joana; Reis, Rui L; Oliveira, Joaquim M; Collins, Maurice N.
  • Murphy CA; Stokes Laboratories, Bernal Institute, School of Engineering, University of Limerick, Limerick V94 PC82, Ireland; email: maurice.collins@ul.ie.
  • Garg AK; Manufacturing Technology and Innovation Global Supply Chain, Johnson & Johnson, Bridgewater, New Jersey 08807, USA.
  • Silva-Correia J; 3B's Research Group, I3B's: Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho and Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, 4805-017 Barco, Guimarães, Portugal.
  • Reis RL; ICVS/3B's: PT Government Associate Laboratory, 4710-057 Braga, Guimarães, Portugal.
  • Oliveira JM; 3B's Research Group, I3B's: Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho and Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, 4805-017 Barco, Guimarães, Portugal.
  • Collins MN; ICVS/3B's: PT Government Associate Laboratory, 4710-057 Braga, Guimarães, Portugal.
Annu Rev Biomed Eng ; 21: 495-521, 2019 06 04.
Article en En | MEDLINE | ID: mdl-30969794
ABSTRACT
The treatment of meniscus injuries has recently been facing a paradigm shift toward the field of tissue engineering, with the aim of regenerating damaged and diseased menisci as opposed to current treatment techniques. This review focuses on the structure and mechanics associated with the meniscus. The meniscus is defined in terms of its biological structure and composition. Biomechanics of the meniscus are discussed in detail, as an understanding of the mechanics is fundamental for the development of new meniscal treatment strategies. Key meniscal characteristics such as biological function, damage (tears), and disease are critically analyzed. The latest technologies behind meniscal repair and regeneration are assessed.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoartritis de la Rodilla / Ingeniería de Tejidos / Lesiones de Menisco Tibial Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Osteoartritis de la Rodilla / Ingeniería de Tejidos / Lesiones de Menisco Tibial Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article