Delayed remission following sequential infusion of humanized CD19- and CD22-modified CAR-T cells in a patient with relapsed/refractory acute lymphoblastic leukemia and prior exposure to murine-derived CD19-directed CAR-T cells.

Yang, Fei; Zhang, Jian; Zhang, Xinyou; Tian, Mengli; Wang, Jingjing; Kang, Liqing; Qiu, Huiying; Wu, Depei

Yang, Fei; Zhang, Jian; Zhang, Xinyou; Tian, Mengli; Wang, Jingjing; Kang, Liqing; Qiu, Huiying; Wu, Depei.

Yang F; Department of Hematology, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China, pursueyf08@126.com.
Zhang J; Department of Hematology, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China, pursueyf08@126.com.
Zhang X; Department of Hematology, The Second Clinical Medical College of Jinan University (Shenzhen People's Hospital), Jinan University, Shenzhen, Guangdong Province, People's Republic of China.
Tian M; Department of Hematology, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China, pursueyf08@126.com.
Wang J; Department of Hematology, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China, pursueyf08@126.com.
Kang L; Institute of Biomedical Engineering and Technology, Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, People's Republic of China.
Qiu H; Department of Hematology, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China, pursueyf08@126.com.
Wu D; Department of Hematology, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China, pursueyf08@126.com.

Onco Targets Ther ; 12: 2187-2191, 2019.

Article en En | MEDLINE | ID: mdl-30988623