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Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae.
Parisi, Cristina; Failla, Mariacristina; Fraix, Aurore; Rolando, Barbara; Gianquinto, Eleonora; Spyrakis, Francesca; Gazzano, Elena; Riganti, Chiara; Lazzarato, Loretta; Fruttero, Roberta; Gasco, Alberto; Sortino, Salvatore.
  • Parisi C; Laboratory of Photochemistry, Department of Drug Sciences, University of Catania, 95125, Catania, Italy.
  • Failla M; Laboratory of Photochemistry, Department of Drug Sciences, University of Catania, 95125, Catania, Italy.
  • Fraix A; Department of Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy.
  • Rolando B; Laboratory of Photochemistry, Department of Drug Sciences, University of Catania, 95125, Catania, Italy.
  • Gianquinto E; Department of Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy.
  • Spyrakis F; Department of Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy.
  • Gazzano E; Department of Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy.
  • Riganti C; Department of Oncology, University of Torino, Via Santena 5/bis, 10126, Torino, Italy.
  • Lazzarato L; Department of Oncology, University of Torino, Via Santena 5/bis, 10126, Torino, Italy.
  • Fruttero R; Department of Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy.
  • Gasco A; Department of Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy.
  • Sortino S; Department of Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy.
Chemistry ; 25(47): 11080-11084, 2019 Aug 22.
Article en En | MEDLINE | ID: mdl-31074543
Two novel NO photodonors (NOPDs) based on BODIPY and Rhodamine antennae activatable with the highly biocompatible green light are reported. Both NOPDs exhibit considerable fluorescence emission and release NO with remarkable quantum efficiencies. The combination of the photoreleasing and emissive performance for both compounds is superior to those exhibited by other NOPDs based on similar light-harvesting centres, making them very intriguing for image-guided phototherapeutic applications. Preliminary biological data prove their easy visualization in cell environment due to the intense green and orange-red fluorescence and their photodynamic action on cancer cells due to the NO photo-liberated.
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2019 Tipo del documento: Article