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TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response.
Wang, Peng; Deng, Jianwen; Dong, Jie; Liu, Jianghong; Bigio, Eileen H; Mesulam, Marsel; Wang, Tao; Sun, Lei; Wang, Li; Lee, Alan Yueh-Luen; McGee, Warren A; Chen, Xiaoping; Fushimi, Kazuo; Zhu, Li; Wu, Jane Y.
  • Wang P; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Deng J; University of Chinese Academy of Sciences, Beijing, China.
  • Dong J; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Liu J; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Bigio EH; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Mesulam M; Department of Pathology & Neurology, The Cognitive Neurology & Alzheimer's Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
  • Wang T; Department of Pathology & Neurology, The Cognitive Neurology & Alzheimer's Disease Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
  • Sun L; National Institute of Biological Sciences, Beijing, China.
  • Wang L; Center for Biological Imaging, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Lee AY; Center for Biological Imaging, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • McGee WA; National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan.
  • Chen X; Department of Neurology, Center for Genetic Medicine, Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
  • Fushimi K; Department of Neurology, Center for Genetic Medicine, Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
  • Zhu L; Department of Neurology, Center for Genetic Medicine, Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
  • Wu JY; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
PLoS Genet ; 15(5): e1007947, 2019 05.
Article en En | MEDLINE | ID: mdl-31100073

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Mitocondriales / Proteasas ATP-Dependientes / Proteínas de Unión al ADN / Degeneración Lobar Frontotemporal / Proteinopatías TDP-43 / Respuesta de Proteína Desplegada / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Mitocondriales / Proteasas ATP-Dependientes / Proteínas de Unión al ADN / Degeneración Lobar Frontotemporal / Proteinopatías TDP-43 / Respuesta de Proteína Desplegada / Esclerosis Amiotrófica Lateral Límite: Animals / Humans Idioma: En Año: 2019 Tipo del documento: Article