Detection of lung transplant rejection in a rat model using hyperpolarized [1-<sup>13</sup> C] pyruvate-based metabolic imaging.

Siddiqui, Sarmad; Habertheuer, Andreas; Xin, Yi; Pourfathi, Mehrdad; Tao, Jian-Qin; Hamedani, Hooman; Kadlecek, Stephen; Duncan, Ian; Vallabhajosyula, Prashanth; Naji, Ali; Chatterjee, Shampa; Rizi, Rahim

Detection of lung transplant rejection in a rat model using hyperpolarized [1-¹³ C] pyruvate-based metabolic imaging.

Siddiqui, Sarmad; Habertheuer, Andreas; Xin, Yi; Pourfathi, Mehrdad; Tao, Jian-Qin; Hamedani, Hooman; Kadlecek, Stephen; Duncan, Ian; Vallabhajosyula, Prashanth; Naji, Ali; Chatterjee, Shampa; Rizi, Rahim.

Siddiqui S; Department of Radiology, University of Pennsylvania, PA, USA.
Habertheuer A; Department of Surgery, University of Pennsylvania, PA, USA.
Xin Y; Department of Radiology, University of Pennsylvania, PA, USA.
Pourfathi M; Department of Radiology, University of Pennsylvania, PA, USA.
Tao JQ; Institute for Environmental Medicine, University of Pennsylvania, PA, USA.
Hamedani H; Department of Radiology, University of Pennsylvania, PA, USA.
Kadlecek S; Department of Radiology, University of Pennsylvania, PA, USA.
Duncan I; Department of Radiology, University of Pennsylvania, PA, USA.
Vallabhajosyula P; Department of Surgery, University of Pennsylvania, PA, USA.
Naji A; Department of Surgery, University of Pennsylvania, PA, USA.
Chatterjee S; Institute for Environmental Medicine, University of Pennsylvania, PA, USA.
Rizi R; Department of Radiology, University of Pennsylvania, PA, USA.

NMR Biomed ; 32(8): e4107, 2019 08.

Article en En | MEDLINE | ID: mdl-31112351

Asunto(s)

Isótopos de Carbono/metabolismo; Rechazo de Injerto/metabolismo; Trasplante de Pulmón/efectos adversos; Imagen Molecular; Ácido Pirúvico/metabolismo; Animales; Biomarcadores/metabolismo; Rechazo de Injerto/inmunología; Ácido Láctico/metabolismo; Pulmón/diagnóstico por imagen; Imagen por Resonancia Magnética; Masculino; Modelos Animales; Tamaño de los Órganos; Peroxidasa/metabolismo; Ratas Wistar; Linfocitos T/metabolismo; Tomografía Computarizada por Rayos X

Palabras clave

Allogeneic; [1-13]C pyruvate; chemical shift imaging; computed tomography; hyperpolarized carbon-13; lactate-to-pyruvate ratio; lung transplantation; syngeneic

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Isótopos de Carbono / Trasplante de Pulmón / Ácido Pirúvico / Imagen Molecular / Rechazo de Injerto Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article

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