The association between cone density and visual function in the macula of patients with retinitis pigmentosa.
Graefes Arch Clin Exp Ophthalmol
; 257(9): 1841-1846, 2019 Sep.
Article
en En
| MEDLINE
| ID: mdl-31172265
ABSTRACT
PURPOSE:
We observed cone photoreceptors by using adaptive optics (AO) fundus camera and optical coherence tomography (OCT) in patients with retinitis pigmentosa (RP) and examined the correlations between cone photoreceptors and visual function over 2 years.METHODS:
Six patients with RP were studied. All patients underwent measurement using best-corrected decimal visual acuity, OCT, a Humphrey Field Analyzer with the 10-2 test grid pattern, and AO. AO images of the foveal center were obtained using an rtx1™ AO fundus camera, and cone counting was performed at 0.5 mm from the foveal center.RESULTS:
AO detected a decrease of cone density over 2 years in RP patients. However, visual acuity, foveal sensitivity, and photoreceptor thickness were not changed over the 2 years.CONCLUSIONS:
AO images showed a decrease in the number of foveal cone densities over 2 years in patients with RP. AO may shorten the period required to predict the RP progression rate.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Agudeza Visual
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Retinitis Pigmentosa
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Células Fotorreceptoras Retinianas Conos
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Mácula Lútea
Tipo de estudio:
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2019
Tipo del documento:
Article