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Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families.
Lakeman, Inge M M; Hilbers, Florentine S; Rodríguez-Girondo, Mar; Lee, Andrew; Vreeswijk, Maaike P G; Hollestelle, Antoinette; Seynaeve, Caroline; Meijers-Heijboer, Hanne; Oosterwijk, Jan C; Hoogerbrugge, Nicoline; Olah, Edith; Vasen, Hans F A; van Asperen, Christi J; Devilee, Peter.
  • Lakeman IMM; Department of Human Genetics, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
  • Hilbers FS; Department of Human Genetics, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
  • Rodríguez-Girondo M; Breast International Group (BIG), Brussels, Belgium.
  • Lee A; Department of Medical Statistics and Bioinformatics, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
  • Vreeswijk MPG; Public Health and Primary Care, Centre for Cancer Gentic Epidemiology, Cambridge University, Cambridge, UK.
  • Hollestelle A; Department of Human Genetics, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
  • Seynaeve C; Department of Medical Oncology, Erasmus MC Kanker Instituut, Rotterdam, The Netherlands.
  • Meijers-Heijboer H; Department of Medical Oncology, Erasmus MC Kanker Instituut, Rotterdam, The Netherlands.
  • Oosterwijk JC; Department of Clinical Genetics, VU medisch centrum, Amsterdam, The Netherlands.
  • Hoogerbrugge N; Department of Genetics, Universitair Medisch Centrum Groningen, Groningen, The Netherlands.
  • Olah E; Department of Human Genetics, Universitair Medisch Centrum Sint Radboud, Nijmegen, The Netherlands.
  • Vasen HFA; Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.
  • van Asperen CJ; Department of Gastroenterology and Hepatology, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
  • Devilee P; Department of Clinical Genetics, Leids Universitair Medisch Centrum, Leiden, The Netherlands.
J Med Genet ; 56(9): 581-589, 2019 09.
Article en En | MEDLINE | ID: mdl-31186341
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Biomarcadores de Tumor / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple / Estudios de Asociación Genética Tipo de estudio: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Biomarcadores de Tumor / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple / Estudios de Asociación Genética Tipo de estudio: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article