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PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension.
Cao, Yapeng; Zhang, Xiaoyu; Wang, Lina; Yang, Qiuhua; Ma, Qian; Xu, Jiean; Wang, Jingjing; Kovacs, Laszlo; Ayon, Ramon J; Liu, Zhiping; Zhang, Min; Zhou, Yaqi; Zeng, Xianqiu; Xu, Yiming; Wang, Yong; Fulton, David J; Weintraub, Neal L; Lucas, Rudolf; Dong, Zheng; Yuan, Jason X-J; Sullivan, Jennifer C; Meadows, Louise; Barman, Scott A; Wu, Chaodong; Quan, Junmin; Hong, Mei; Su, Yunchao; Huo, Yuqing.
  • Cao Y; Drug Discovery Center, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Zhang X; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Wang L; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Yang Q; Vascular Biology Center, Augusta University, Augusta, GA 30912.
  • Ma Q; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912.
  • Xu J; Drug Discovery Center, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Wang J; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Kovacs L; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Ayon RJ; Vascular Biology Center, Augusta University, Augusta, GA 30912.
  • Liu Z; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912.
  • Zhang M; Drug Discovery Center, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Zhou Y; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Zeng X; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Xu Y; Vascular Biology Center, Augusta University, Augusta, GA 30912.
  • Wang Y; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912.
  • Fulton DJ; Drug Discovery Center, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Weintraub NL; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Lucas R; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Dong Z; Vascular Biology Center, Augusta University, Augusta, GA 30912.
  • Yuan JX; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912.
  • Sullivan JC; Drug Discovery Center, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Meadows L; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Barman SA; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Wu C; Vascular Biology Center, Augusta University, Augusta, GA 30912.
  • Quan J; Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912.
  • Hong M; Drug Discovery Center, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Su Y; State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
  • Huo Y; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 518055 Shenzhen, China.
Proc Natl Acad Sci U S A ; 116(27): 13394-13403, 2019 07 02.
Article en En | MEDLINE | ID: mdl-31213542

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfofructoquinasa-2 / Glucólisis / Hipertensión Pulmonar / Pulmón Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfofructoquinasa-2 / Glucólisis / Hipertensión Pulmonar / Pulmón Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article