Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome.

Kotch, Chelsea; Barrett, David; Teachey, David T

Kotch, Chelsea; Barrett, David; Teachey, David T.

Kotch C; a Department of Pediatrics, Division of Oncology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine , Philadelphia , PA , USA.
Barrett D; a Department of Pediatrics, Division of Oncology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine , Philadelphia , PA , USA.
Teachey DT; a Department of Pediatrics, Division of Oncology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine , Philadelphia , PA , USA.

Expert Rev Clin Immunol ; 15(8): 813-822, 2019 08.

Article en En | MEDLINE | ID: mdl-31219357

Asunto(s)

Anticuerpos Monoclonales Humanizados/uso terapéutico; Síndrome de Liberación de Citoquinas/tratamiento farmacológico; Inmunoterapia Adoptiva/métodos; Leucemia-Linfoma Linfoblástico de Células Precursoras B/terapia; Receptores de Antígenos de Linfocitos T/inmunología; Receptores Quiméricos de Antígenos/inmunología; Síndrome de Liberación de Citoquinas/inmunología; Humanos; Receptores de Interleucina-6/antagonistas & inhibidores; Receptores de Interleucina-6/inmunología; Resultado del Tratamiento

Palabras clave

Chimeric antigen receptor T cells (CAR T); chimeric antigen receptor T cell related encephalopathy syndrome (CRES); cytokine release syndrome (CRS); hemophagocytic lymphohistiocytosis (HLH); immune effector cell-associated neurotoxicity syndrome (ICANS); interleukin 6 (IL-6); neurotoxicity (NT); tisagenlecleucel; tocilizumab

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Leucemia-Linfoma Linfoblástico de Células Precursoras B / Inmunoterapia Adoptiva / Anticuerpos Monoclonales Humanizados / Receptores Quiméricos de Antígenos / Síndrome de Liberación de Citoquinas Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google