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Microglial Trem2 induces synaptic impairment at early stage and prevents amyloidosis at late stage in APP/PS1 mice.
Sheng, Liang; Chen, Mingming; Cai, Keshu; Song, Yu; Yu, Dongsheng; Zhang, Hui; Xu, Guangxu.
  • Sheng L; Department of Pharmacology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China.
  • Chen M; Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, Nanjing, China.
  • Cai K; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Song Y; Pharmacy College, Xinxiang Medical University, Xinxiang, China.
  • Yu D; Department of Pharmacology, School of Basic Medical Science, Nanjing Medical University, Nanjing, China.
  • Zhang H; Pharmacy College, Xinxiang Medical University, Xinxiang, China.
  • Xu G; Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
FASEB J ; 33(9): 10425-10442, 2019 09.
Article en En | MEDLINE | ID: mdl-31219699
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sinapsis / Glicoproteínas de Membrana / Receptores Inmunológicos / Precursor de Proteína beta-Amiloide / Placa Amiloide / Presenilina-1 / Enfermedad de Alzheimer / Amiloidosis Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sinapsis / Glicoproteínas de Membrana / Receptores Inmunológicos / Precursor de Proteína beta-Amiloide / Placa Amiloide / Presenilina-1 / Enfermedad de Alzheimer / Amiloidosis Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article