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Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice.
Moreau, Dimitri; Vacca, Fabrizio; Vossio, Stefania; Scott, Cameron; Colaco, Alexandria; Paz Montoya, Jonathan; Ferguson, Charles; Damme, Markus; Moniatte, Marc; Parton, Robert G; Platt, Frances M; Gruenberg, Jean.
  • Moreau D; Department of Biochemistry, University of Geneva, Geneva 4, Switzerland.
  • Vacca F; Department of Biochemistry, University of Geneva, Geneva 4, Switzerland.
  • Vossio S; Department of Biochemistry, University of Geneva, Geneva 4, Switzerland.
  • Scott C; Department of Biochemistry, University of Geneva, Geneva 4, Switzerland.
  • Colaco A; Department of Pharmacology, University of Oxford, Oxford, UK.
  • Paz Montoya J; Mass Spectrometry Core Facility, EPFL, Lausanne, Switzerland.
  • Ferguson C; Institute for Molecular Bioscience and Center for Microscopy and Microanalysis, University of Queensland, Brisbane, Qld, Australia.
  • Damme M; Biochemisches Institut, Christian-Albrechts-Universität, Kiel, Germany.
  • Moniatte M; Mass Spectrometry Core Facility, EPFL, Lausanne, Switzerland.
  • Parton RG; Institute for Molecular Bioscience and Center for Microscopy and Microanalysis, University of Queensland, Brisbane, Qld, Australia.
  • Platt FM; Department of Pharmacology, University of Oxford, Oxford, UK.
  • Gruenberg J; Department of Biochemistry, University of Geneva, Geneva 4, Switzerland.
EMBO Rep ; 20(7): e47055, 2019 07.
Article en En | MEDLINE | ID: mdl-31267706
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Endosomas / Lisofosfolípidos / Colesterol / Monoglicéridos / Enfermedad de Niemann-Pick Tipo C Límite: Animals / Female / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperidinas / Endosomas / Lisofosfolípidos / Colesterol / Monoglicéridos / Enfermedad de Niemann-Pick Tipo C Límite: Animals / Female / Humans / Male Idioma: En Año: 2019 Tipo del documento: Article