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Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and ß-globin gene promoters.
Breveglieri, Giulia; Salvatori, Francesca; Finotti, Alessia; Cosenza, Lucia Carmela; Zuccato, Cristina; Bianchi, Nicoletta; Breda, Laura; Rivella, Stefano; Bresciani, Alberto; Bisbocci, Monica; Borgatti, Monica; Gambari, Roberto.
  • Breveglieri G; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.
  • Salvatori F; Biotechnology Center, University of Ferrara, 44121, Ferrara, Italy.
  • Finotti A; Department of Chemical and Pharmaceutical Sciences, University of Ferrara, 44121, Ferrara, Italy.
  • Cosenza LC; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.
  • Zuccato C; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.
  • Bianchi N; Biotechnology Center, University of Ferrara, 44121, Ferrara, Italy.
  • Breda L; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, University of Ferrara, Via Fossato di Mortara 74, 44121, Ferrara, Italy.
  • Rivella S; Department of Biomedical Sciences and Specialist Surgery, Section of Biochemistry, Molecular Biology and Medical Genetics, University of Ferrara, 44121, Ferrara, Italy.
  • Bresciani A; Hematology Division, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Bisbocci M; Hematology Division, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Borgatti M; IRBM Science Park SpA, 00071, Pomezia (Rome), Italy.
  • Gambari R; IRBM Science Park SpA, 00071, Pomezia (Rome), Italy.
Anal Bioanal Chem ; 411(29): 7669-7680, 2019 Nov.
Article en En | MEDLINE | ID: mdl-31273412
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transcripción Genética / Técnicas Biosensibles / Diferenciación Celular / Regiones Promotoras Genéticas / Eritrocitos / Globinas beta / Gamma-Globinas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transcripción Genética / Técnicas Biosensibles / Diferenciación Celular / Regiones Promotoras Genéticas / Eritrocitos / Globinas beta / Gamma-Globinas / Ensayos Analíticos de Alto Rendimiento Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article