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Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.
Kawamura, Yusuke; Nakaoka, Hirofumi; Nakayama, Akiyoshi; Okada, Yukinori; Yamamoto, Ken; Higashino, Toshihide; Sakiyama, Masayuki; Shimizu, Toru; Ooyama, Hiroshi; Ooyama, Keiko; Nagase, Mitsuo; Hidaka, Yuji; Shirahama, Yuko; Hosomichi, Kazuyoshi; Nishida, Yuichiro; Shimoshikiryo, Ippei; Hishida, Asahi; Katsuura-Kamano, Sakurako; Shimizu, Seiko; Kawaguchi, Makoto; Uemura, Hirokazu; Ibusuki, Rie; Hara, Megumi; Naito, Mariko; Takao, Mikiya; Nakajima, Mayuko; Iwasawa, Satoko; Nakashima, Hiroshi; Ohnaka, Keizo; Nakamura, Takahiro; Stiburkova, Blanka; Merriman, Tony R; Nakatochi, Masahiro; Ichihara, Sahoko; Yokota, Mitsuhiro; Takada, Tappei; Saitoh, Tatsuya; Kamatani, Yoichiro; Takahashi, Atsushi; Arisawa, Kokichi; Takezaki, Toshiro; Tanaka, Keitaro; Wakai, Kenji; Kubo, Michiaki; Hosoya, Tatsuo; Ichida, Kimiyoshi; Inoue, Ituro; Shinomiya, Nariyoshi; Matsuo, Hirotaka.
  • Kawamura Y; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Nakaoka H; Department of General Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Nakayama A; Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan.
  • Okada Y; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Yamamoto K; Medical Squadron, Air Base Group, Western Aircraft Control and Warning Wing, Japan Air Self-Defense Force, Kasuga, Fukuoka, Japan.
  • Higashino T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
  • Sakiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.
  • Shimizu T; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Osaka, Japan.
  • Ooyama H; Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
  • Ooyama K; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Nagase M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Hidaka Y; Department of Defense Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Shirahama Y; Midorigaoka Hospital, Takatsuki, Osaka, Japan.
  • Hosomichi K; Kyoto Industrial Health Association, Kyoto, Japan.
  • Nishida Y; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Shimoshikiryo I; Ryougoku East Gate Clinic, Tokyo, Japan.
  • Hishida A; Nagase Clinic, Tokyo, Japan.
  • Katsuura-Kamano S; Akasaka Central Clinic, Tokyo, Japan.
  • Shimizu S; Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
  • Kawaguchi M; Department of Bioinformatics and Genomics, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan.
  • Uemura H; Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan.
  • Ibusuki R; Department of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
  • Hara M; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Naito M; Department of Preventive Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan.
  • Takao M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Nakajima M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Iwasawa S; Department of Urology, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Nakashima H; Department of Preventive Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan.
  • Ohnaka K; Department of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
  • Nakamura T; Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan.
  • Stiburkova B; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Merriman TR; Department of Oral Epidemiology, Hiroshima University Graduate School of Biomedical & Health Sciences, Hiroshima, Japan.
  • Nakatochi M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Ichihara S; Department of Surgery, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Yokota M; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Takada T; Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Saitoh T; Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Kamatani Y; Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Takahashi A; Laboratory for Mathematics, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Arisawa K; Institute of Rheumatology, Prague, Czech Republic.
  • Takezaki T; Department of Pediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
  • Tanaka K; Department of Biochemisty, University of Otago, Dunedin, New Zealand.
  • Wakai K; Data Science Division, Data Coordinating Center, Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Aichi, Japan.
  • Kubo M; Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Hosoya T; Department of Genome Science, School of Dentistry, Aichi Gakuin University, Nagoya, Aichi, Japan.
  • Ichida K; Department of Pharmacy, the University of Tokyo Hospital, Tokyo, Japan.
  • Inoue I; Laboratory of Bioresponse Regulation, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan.
  • Shinomiya N; Division of Inflammation Biology, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
  • Matsuo H; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.
Ann Rheum Dis ; 78(10): 1430-1437, 2019 10.
Article en En | MEDLINE | ID: mdl-31289104
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Dedos de Zinc / Hiperuricemia / MicroARNs / Contactinas / Gota Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Adult / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Dedos de Zinc / Hiperuricemia / MicroARNs / Contactinas / Gota Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Adult / Humans / Male / Middle aged Idioma: En Año: 2019 Tipo del documento: Article