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Configurationally Stabilized Analogs of M. ulcerans Exotoxins Mycolactones A and B Reveal the Importance of Side Chain Geometry for Mycolactone Virulence.
Gehringer, Matthias; Mäder, Patrick; Gersbach, Philipp; Pfeiffer, Bernhard; Scherr, Nicole; Dangy, Jean-Pierre; Pluschke, Gerd; Altmann, Karl-Heinz.
  • Gehringer M; Swiss Federal Institute of Technology (ETH) Zürich , Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences , Vladimir-Prelog-Weg 4 , 8093 Zürich , Switzerland.
  • Mäder P; Swiss Federal Institute of Technology (ETH) Zürich , Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences , Vladimir-Prelog-Weg 4 , 8093 Zürich , Switzerland.
  • Gersbach P; Swiss Federal Institute of Technology (ETH) Zürich , Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences , Vladimir-Prelog-Weg 4 , 8093 Zürich , Switzerland.
  • Pfeiffer B; Swiss Federal Institute of Technology (ETH) Zürich , Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences , Vladimir-Prelog-Weg 4 , 8093 Zürich , Switzerland.
  • Scherr N; Swiss Tropical and Public Health Institute , Socinstrasse 57 , 4002 Basel , Switzerland.
  • Dangy JP; Swiss Tropical and Public Health Institute , Socinstrasse 57 , 4002 Basel , Switzerland.
  • Pluschke G; Swiss Tropical and Public Health Institute , Socinstrasse 57 , 4002 Basel , Switzerland.
  • Altmann KH; Swiss Federal Institute of Technology (ETH) Zürich , Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences , Vladimir-Prelog-Weg 4 , 8093 Zürich , Switzerland.
Org Lett ; 21(15): 5853-5857, 2019 08 02.
Article en En | MEDLINE | ID: mdl-31295000
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Virulencia / Macrólidos / Mycobacterium ulcerans / Exotoxinas Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Virulencia / Macrólidos / Mycobacterium ulcerans / Exotoxinas Idioma: En Año: 2019 Tipo del documento: Article