Identification of a novel diagnostic gene expression signature to discriminate uterine leiomyoma from leiomyosarcoma.

Adams, Crystal L; Dimitrova, Irina; Post, Miriam D; Gibson, Lacey; Spillman, Monique A; Behbakht, Kian; Bradford, Andrew P

Adams, Crystal L; Dimitrova, Irina; Post, Miriam D; Gibson, Lacey; Spillman, Monique A; Behbakht, Kian; Bradford, Andrew P.

Adams CL; Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Dimitrova I; Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA; Department of Obstetrics and Gynecology, Division Gynecologic Oncology, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Post MD; Department of Pathology, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Gibson L; Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Spillman MA; Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA; Department of Obstetrics and Gynecology, Division Gynecologic Oncology, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Behbakht K; Department of Obstetrics and Gynecology, Division Gynecologic Oncology, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Bradford AP; Department of Obstetrics and Gynecology, Division of Reproductive Sciences, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA. Electronic address: Andy.Bradford@ucdenver.edu.

Exp Mol Pathol ; 110: 104284, 2019 10.

Article en En | MEDLINE | ID: mdl-31301306

Asunto(s)

Biomarcadores de Tumor/genética; Perfilación de la Expresión Génica; Regulación Neoplásica de la Expresión Génica; Leiomioma/genética; Leiomiosarcoma/genética; Neoplasias Uterinas/genética; Anciano; Biomarcadores de Tumor/metabolismo; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Proteína 1 Similar a Quitinasa-3/genética; Proteína 1 Similar a Quitinasa-3/metabolismo; Proteínas del Citoesqueleto/genética; Proteínas del Citoesqueleto/metabolismo; Diagnóstico Diferencial; Femenino; Humanos; Oxidorreductasas Intramoleculares; Leiomioma/diagnóstico; Leiomioma/metabolismo; Leiomiosarcoma/diagnóstico; Leiomiosarcoma/metabolismo; Proteínas Asociadas a Microtúbulos/genética; Proteínas Asociadas a Microtúbulos/metabolismo; Persona de Mediana Edad; Proteínas de Unión al ARN/genética; Proteínas de Unión al ARN/metabolismo; Sensibilidad y Especificidad; Neoplasias Uterinas/diagnóstico; Neoplasias Uterinas/metabolismo

Palabras clave

Diagnosis; Gene expression; Leiomyoma; Leiomyosarcoma; Molecular profiling

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Uterinas / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Perfilación de la Expresión Génica / Leiomioma / Leiomiosarcoma Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Female / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article

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