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A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump PfATP4.
Gilson, Paul R; Kumarasingha, Rasika; Thompson, Jennifer; Zhang, Xinxin; Penington, Jocelyn Sietsma; Kalhor, Robabeh; Bullen, Hayley E; Lehane, Adele M; Dans, Madeline G; de Koning-Ward, Tania F; Holien, Jessica K; Soares da Costa, Tatiana P; Hulett, Mark D; Buskes, Melissa J; Crabb, Brendan S; Kirk, Kiaran; Papenfuss, Anthony T; Cowman, Alan F; Abbott, Belinda M.
  • Gilson PR; Burnet Institute, Melbourne, Victoria, 3004, Australia. paul.gilson@burnet.edu.au.
  • Kumarasingha R; Monash University, Melbourne, Victoria, 3800, Australia. paul.gilson@burnet.edu.au.
  • Thompson J; Burnet Institute, Melbourne, Victoria, 3004, Australia.
  • Zhang X; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.
  • Penington JS; Research School of Biology, Australian National University, Canberra, ACT, 2601, Australia.
  • Kalhor R; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, 3052, Australia.
  • Bullen HE; La Trobe University, Melbourne, Victoria, 3086, Australia.
  • Lehane AM; Burnet Institute, Melbourne, Victoria, 3004, Australia.
  • Dans MG; Research School of Biology, Australian National University, Canberra, ACT, 2601, Australia.
  • de Koning-Ward TF; Burnet Institute, Melbourne, Victoria, 3004, Australia.
  • Holien JK; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.
  • Soares da Costa TP; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.
  • Hulett MD; St. Vincent's Institute of Medical Research, Melbourne, Victoria, 3065, Australia.
  • Buskes MJ; La Trobe University, Melbourne, Victoria, 3086, Australia.
  • Crabb BS; La Trobe University, Melbourne, Victoria, 3086, Australia.
  • Kirk K; La Trobe University, Melbourne, Victoria, 3086, Australia.
  • Papenfuss AT; Burnet Institute, Melbourne, Victoria, 3004, Australia.
  • Cowman AF; Monash University, Melbourne, Victoria, 3800, Australia.
  • Abbott BM; University of Melbourne, Melbourne, Victoria, 3010, Australia.
Sci Rep ; 9(1): 10292, 2019 07 16.
Article en En | MEDLINE | ID: mdl-31311978
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / ATPasa Intercambiadora de Sodio-Potasio / Eritrocitos / Isoquinolinas Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plasmodium falciparum / ATPasa Intercambiadora de Sodio-Potasio / Eritrocitos / Isoquinolinas Idioma: En Año: 2019 Tipo del documento: Article