Genotyping Approach for Potential Common Source of Enterocytozoon bieneusi Infection in Hematology Unit.
Emerg Infect Dis
; 25(9): 1625-1631, 2019 09.
Article
en En
| MEDLINE
| ID: mdl-31441425
ABSTRACT
Microsporidiosis is a fungal infection that generally causes digestive disorders, especially in immunocompromised hosts. Over a 4-day period in January 2018, 3 patients with hematologic malignancies who were admitted to the hematology unit of a hospital in France received diagnoses of Enterocytozoon bieneusi microsporidiosis. This unusually high incidence was investigated by sequence analysis at the internal transcribed spacer rDNA locus and then by 3 microsatellites and 1 minisatellite for multilocus genotyping. The 3 isolates had many sequence similarities and belonged to a new genotype closely related to genotype C. In addition, multilocus genotyping showed high genetic distances with all the other strains collected from epidemiologically unrelated persons; none of these strains belonged to the new genotype. These data confirm the epidemiologic link among the 3 patients and support a common source of infection.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Microsporidiosis
/
Neoplasias Hematológicas
/
Enterocytozoon
Límite:
Humans
País como asunto:
Europa
Idioma:
En
Año:
2019
Tipo del documento:
Article