Interplay between substrate recognition, 5' end tRNA processing and methylation activity of human mitochondrial RNase P.

Karasik, Agnes; Fierke, Carol A; Koutmos, Markos

Karasik, Agnes; Fierke, Carol A; Koutmos, Markos.

Karasik A; Department of Biochemistry and Molecular Biology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.
Fierke CA; Department of Chemistry, Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.
Koutmos M; Department of Chemistry, Program in Biophysics, University of Michigan, Ann Arbor, Michigan 48109, USA.

RNA ; 25(12): 1646-1660, 2019 12.

Article en En | MEDLINE | ID: mdl-31455609

Asunto(s)

Mitocondrias/genética; Procesamiento Postranscripcional del ARN; ARN de Transferencia/genética; ARN de Transferencia/metabolismo; Ribonucleasa P/química; Ribonucleasa P/metabolismo; Humanos; Metilación; Mitocondrias/enzimología; Unión Proteica; ARN de Transferencia/química; Especificidad por Sustrato

Palabras clave

MRPP; PRORP; RNase P; mitochondria; pre-tRNA methylation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN de Transferencia / Procesamiento Postranscripcional del ARN / Ribonucleasa P / Mitocondrias Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article

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