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Exposure-response analysis to inform the optimal dose of veliparib in combination with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer patients.
Nuthalapati, Silpa; Stodtmann, Sven; Shepherd, Stacie Peacock; Ratajczak, Christine K; Mensing, Sven; Menon, Rajeev; Xiong, Hao.
  • Nuthalapati S; Clinical Pharmacology and Pharmacometrics, Department R4PK, AbbVie Inc, Building AP31-3, 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Stodtmann S; Clinical Pharmacology and Pharmacometrics, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
  • Shepherd SP; Oncology Development, AbbVie Inc, North Chicago, IL, USA.
  • Ratajczak CK; Oncology Development, AbbVie Inc, North Chicago, IL, USA.
  • Mensing S; Clinical Pharmacology and Pharmacometrics, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
  • Menon R; Clinical Pharmacology and Pharmacometrics, Department R4PK, AbbVie Inc, Building AP31-3, 1 North Waukegan Road, North Chicago, IL, 60064, USA.
  • Xiong H; Clinical Pharmacology and Pharmacometrics, Department R4PK, AbbVie Inc, Building AP31-3, 1 North Waukegan Road, North Chicago, IL, 60064, USA. hao.xiong@abbvie.com.
Cancer Chemother Pharmacol ; 84(5): 977-986, 2019 Nov.
Article en En | MEDLINE | ID: mdl-31468137
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Texto completo: 1 Ejes tematicos: Pesquisa_clinica Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Protocolos de Quimioterapia Combinada Antineoplásica / Modelos Biológicos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Ejes tematicos: Pesquisa_clinica Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Protocolos de Quimioterapia Combinada Antineoplásica / Modelos Biológicos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article