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CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1-ErbB-PI3K signaling.
Choi, Hee-Joo; Jin, Sora; Cho, Hani; Won, Hee-Young; An, Hee Woon; Jeong, Ga-Young; Park, Young-Un; Kim, Hyung-Yong; Park, Mi Kyung; Son, Taekwon; Min, Kyueng-Whan; Jang, Ki-Seok; Oh, Young-Ha; Lee, Jeong-Yeon; Kong, Gu.
  • Choi HJ; Institute for Bioengineering and Biopharmaceutical Research (IBBR), Hanyang University, Seoul, Korea.
  • Jin S; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Cho H; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Won HY; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • An HW; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Jeong GY; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Park YU; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Kim HY; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Park MK; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Son T; National Cancer Center, Goyang, Korea.
  • Min KW; College of Pharmacy, Seoul National University, Seoul, Korea.
  • Jang KS; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Oh YH; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Lee JY; Department of Pathology, College of Medicine, Hanyang University, Seoul, Korea.
  • Kong G; Department of Medicine, College of Medicine, Hanyang University, Seoul, Korea.
EMBO Rep ; 20(10): e48058, 2019 10 04.
Article en En | MEDLINE | ID: mdl-31468695

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Transducción de Señal / Quinasas Ciclina-Dependientes / Resistencia a Antineoplásicos / Carcinogénesis / Trastuzumab Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Transducción de Señal / Quinasas Ciclina-Dependientes / Resistencia a Antineoplásicos / Carcinogénesis / Trastuzumab Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2019 Tipo del documento: Article