Primary treatment patterns and survival of cervical cancer in Sweden: A population-based Swedish Gynecologic Cancer Group Study.
Gynecol Oncol
; 155(2): 229-236, 2019 11.
Article
en En
| MEDLINE
| ID: mdl-31477283
ABSTRACT
OBJECTIVE:
Survival in cervical cancer has improved little over the last decades. We aimed to elucidate primary treatment patterns and survival.METHODS:
Population-based study of patients included in the Swedish Quality Registry for Gynecologic Cancer diagnosed 2011-2015. Main outcome was 5-year relative survival (RS). Age-standardised RS (AS-RS) was estimated for the total cohort and for the pooled study population of squamous, adenosquamous-, adenocarcinoma.RESULTS:
Median follow-up time was 4.6â¯years. The study population consisted of 2141 patients; 97% of the 2212 patients in the total cohort and the 5-year AS-RS was 71% and 70%, respectively. RS stage IB1 surgery alone 95% vs. 72% for definitive chemoradiotherapy (CT-RT) (pâ¯<â¯0.001). In stage IIA1 74% had CT-RT, and 47% of operated patients received adjuvant (CT)-RT. RS stage IB2 surgically treated 81% (69% received adjuvant (CT)-RT) vs. 76% for (CT)-RT (pâ¯=â¯0.73). RS stage IIB 77% for CT-RTâ¯+â¯brachytherapy (BT), 37% for RTâ¯+â¯BT (pâ¯=â¯0.045) and 27% for RT-BT (pâ¯<â¯0.001). Stages III-IVA; <40% received CT-RTâ¯+â¯BT, RS 45% vs. 18% for RT-BT (RR 4.1, pâ¯<â¯0.001). RS stage IVB 7%.CONCLUSION:
Primary treatment of cervical cancer in Sweden adhered to evidence-based standard of care. Areas of improvement include optimising treatment for stages III-IVA, and avoiding combining surgery and radiotherapy.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias del Cuello Uterino
Tipo de estudio:
Clinical_trials
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Observational_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Middle aged
País como asunto:
Europa
Idioma:
En
Año:
2019
Tipo del documento:
Article