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Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies.
Wei, Spencer C; Anang, Nana-Ama A S; Sharma, Roshan; Andrews, Miles C; Reuben, Alexandre; Levine, Jacob H; Cogdill, Alexandria P; Mancuso, James J; Wargo, Jennifer A; Pe'er, Dana; Allison, James P.
  • Wei SC; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Anang NAS; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Sharma R; Computational and Systems Biology Program, Sloan Kettering Institute, New York, NY 10065.
  • Andrews MC; Department of Applied Physics and Applied Mathematics, Columbia University, New York, NY 10027.
  • Reuben A; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Levine JH; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Cogdill AP; Computational and Systems Biology Program, Sloan Kettering Institute, New York, NY 10065.
  • Mancuso JJ; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Wargo JA; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Pe'er D; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Allison JP; Department of Applied Physics and Applied Mathematics, Columbia University, New York, NY 10027.
Proc Natl Acad Sci U S A ; 116(45): 22699-22709, 2019 11 05.
Article en En | MEDLINE | ID: mdl-31636208
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígeno CTLA-4 / Receptor de Muerte Celular Programada 1 / Inmunoterapia / Neoplasias Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígeno CTLA-4 / Receptor de Muerte Celular Programada 1 / Inmunoterapia / Neoplasias Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article