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A novel compound AB38b attenuates oxidative stress and ECM protein accumulation in kidneys of diabetic mice through modulation of Keap1/Nrf2 signaling.
Du, Lei; Wang, Lei; Wang, Bo; Wang, Jin; Hao, Meng; Chen, Yi-Bing; Li, Xi-Zhi; Li, Yuan; Jiang, Yan-Fei; Li, Cheng-Cheng; Yang, Hao; Gu, Xiao-Ke; Yin, Xiao-Xing; Lu, Qian.
  • Du L; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Wang L; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Wang B; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Wang J; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Hao M; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Chen YB; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Li XZ; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Li Y; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Jiang YF; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Li CC; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Yang H; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Gu XK; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Yin XX; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
  • Lu Q; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China. prairy@126.com.
Acta Pharmacol Sin ; 41(3): 358-372, 2020 Mar.
Article en En | MEDLINE | ID: mdl-31645661
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Morfolinas / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Nefropatías Diabéticas / Factor 2 Relacionado con NF-E2 / Proteína 1 Asociada A ECH Tipo Kelch / Resveratrol / Cetonas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Morfolinas / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Nefropatías Diabéticas / Factor 2 Relacionado con NF-E2 / Proteína 1 Asociada A ECH Tipo Kelch / Resveratrol / Cetonas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2020 Tipo del documento: Article