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Antitumor activity of the poly(ADP-ribose) polymerase inhibitor rucaparib as monotherapy in patients with platinum-sensitive, relapsed, BRCA-mutated, high-grade ovarian cancer, and an update on safety.
Kristeleit, Rebecca S; Oaknin, Ana; Ray-Coquard, Isabelle; Leary, Alexandra; Balmaña, Judith; Drew, Yvette; Oza, Amit M; Shapira-Frommer, Ronnie; Domchek, Susan M; Cameron, Terri; Maloney, Lara; Goble, Sandra; Lorusso, Domenica; Ledermann, Jonathan A; McNeish, Iain A.
  • Kristeleit RS; UCL Cancer Institute, University College London and UCL Hospitals, London, UK r.kristeleit@ucl.ac.uk.
  • Oaknin A; Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
  • Ray-Coquard I; Centre Léon Bérard and University Claude Bernard and Groupe d'Investigateurs Nationaux pour l'Etude des Cancers Ovariens (GINECO), Lyon, France.
  • Leary A; Gustave Roussy Cancer Center, INSERM U981, and GINECO, Villejuif, France.
  • Balmaña J; Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
  • Drew Y; Northern Centre for Cancer Care, Newcastle Hospitals NHS Foundation Trust and Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
  • Oza AM; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
  • Shapira-Frommer R; Chaim Sheba Medical Center, Tel HaShomer, Israel.
  • Domchek SM; Abramson Cancer Center, Basser Center for BRCA, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Cameron T; Clovis Oncology UK Ltd, Cambridge, UK.
  • Maloney L; Clovis Oncology, Inc, Boulder, Colorado, USA.
  • Goble S; Clovis Oncology, Inc, Boulder, Colorado, USA.
  • Lorusso D; Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
  • Ledermann JA; UCL Cancer Institute, University College London and UCL Hospitals, London, UK.
  • McNeish IA; Imperial College London, London, UK.
Int J Gynecol Cancer ; 29(9): 1396-1404, 2019 11.
Article en En | MEDLINE | ID: mdl-31685558
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Indoles Tipo de estudio: Diagnostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Indoles Tipo de estudio: Diagnostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article