HiCBricks: building blocks for efficient handling of large Hi-C datasets.
Bioinformatics
; 2019 Nov 07.
Article
en En
| MEDLINE
| ID: mdl-31697323
ABSTRACT
SUMMARY:
Genome-wide chromosome conformation capture based on high-throughput sequencing (Hi-C) has been widely adopted to study chromatin architecture by generating datasets of ever-increasing complexity and size. HiCBricks offers user-friendly and efficient solutions for handling large high-resolution Hi-C datasets. The package provides an R/Bioconductor framework with the bricks to build more complex data analysis pipelines and algorithms. HiCBricks already incorporates functions for calling domain boundaries and functions for high quality data visualization.AVAILABILITY:
http//bioconductor.org/packages/devel/bioc/html/HiCBricks.html. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Banco de datos:
MEDLINE
Idioma:
En
Año:
2019
Tipo del documento:
Article