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Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.
Hashimoto, Kosuke; Kouno, Tsukasa; Ikawa, Tomokatsu; Hayatsu, Norihito; Miyajima, Yurina; Yabukami, Haruka; Terooatea, Tommy; Sasaki, Takashi; Suzuki, Takahiro; Valentine, Matthew; Pascarella, Giovanni; Okazaki, Yasushi; Suzuki, Harukazu; Shin, Jay W; Minoda, Aki; Taniuchi, Ichiro; Okano, Hideyuki; Arai, Yasumichi; Hirose, Nobuyoshi; Carninci, Piero.
  • Hashimoto K; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Kouno T; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Ikawa T; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Hayatsu N; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Miyajima Y; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Yabukami H; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Terooatea T; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Sasaki T; Centre for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan 160-8582.
  • Suzuki T; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Valentine M; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Pascarella G; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Okazaki Y; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Suzuki H; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Shin JW; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Minoda A; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Taniuchi I; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045.
  • Okano H; Centre for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan 160-8582.
  • Arai Y; Centre for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan 160-8582.
  • Hirose N; Centre for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan 160-8582 hirosen@z8.keio.jp carninci@riken.jp.
  • Carninci P; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan 230-0045; hirosen@z8.keio.jp carninci@riken.jp.
Proc Natl Acad Sci U S A ; 116(48): 24242-24251, 2019 11 26.
Article en En | MEDLINE | ID: mdl-31719197
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Año: 2019 Tipo del documento: Article