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Combined mTORC1/mTORC2 inhibition blocks growth and induces catastrophic macropinocytosis in cancer cells.
Srivastava, Ritesh K; Li, Changzhao; Khan, Jasim; Banerjee, Nilam Sanjib; Chow, Louise T; Athar, Mohammad.
  • Srivastava RK; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Li C; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Khan J; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Banerjee NS; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Chow LT; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294 ltchow@uab.edu mohammadathar@uabmc.edu.
  • Athar M; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294; ltchow@uab.edu mohammadathar@uabmc.edu.
Proc Natl Acad Sci U S A ; 116(49): 24583-24592, 2019 12 03.
Article en En | MEDLINE | ID: mdl-31732667
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pinocitosis / Purinas / Triazinas / Diana Mecanicista del Complejo 1 de la Rapamicina / Diana Mecanicista del Complejo 2 de la Rapamicina / Imidazoles / Indoles / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2019 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pinocitosis / Purinas / Triazinas / Diana Mecanicista del Complejo 1 de la Rapamicina / Diana Mecanicista del Complejo 2 de la Rapamicina / Imidazoles / Indoles / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Año: 2019 Tipo del documento: Article