Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement.

Alexander, Jes; Findlay, Gregory M; Kircher, Martin; Shendure, Jay

Alexander, Jes; Findlay, Gregory M; Kircher, Martin; Shendure, Jay.

Alexander J; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Findlay GM; Department of Radiation Oncology, School of Medicine, University of Washington, Seattle, WA, USA.
Kircher M; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA.

BMC Biol ; 17(1): 90, 2019 11 18.

Article en En | MEDLINE | ID: mdl-31739790

Asunto(s)

Sistemas CRISPR-Cas/genética; Ctenóforos/genética; Edición Génica/métodos; Genoma/genética; Animales; Secuencia de Bases; Epigenoma/genética

Palabras clave

CRISPR/Cas9; DNA methylation; Epigenome editing; Gene silencing; Genome editing; HPRT1

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genoma / Ctenóforos / Sistemas CRISPR-Cas / Edición Génica Límite: Animals Idioma: En Año: 2019 Tipo del documento: Article

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