Evidence of Saffold virus circulation in Italy provided through environmental surveillance.
Lett Appl Microbiol
; 70(2): 102-108, 2020 Feb.
Article
en En
| MEDLINE
| ID: mdl-31742735
ABSTRACT
Saffold virus (SAFV) is an emerging human cardiovirus associated with respiratory and gastrointestinal infection, and, more recently, to symptoms related to the endocrine, cardiovascular, and neurological systems. Information about SAFV circulation in Italy is scarce. In order to provide insights into the epidemiology of SAFV in Italy, 141 raw sewage samples collected throughout Italy were tested using broad-range nested RT-PCR primers targeting the 5'-NC region. Seven samples (5·0%) were confirmed as SAFV in samples collected in North, Centre and Southern Italy. Typing was attempted through amplification of the VP1 coding region, using both published and newly designed primers, and one sample was characterized as SAFV-2. SIGNIFICANCE AND IMPACT OF THE STUDY Prevalence, genetic diversity and geographic distribution of SAFV in Italy is currently unknown. This study represents the first detection of SAFV in sewage samples in Italy, suggesting that it is circulating in the population despite lack of clinical reporting. Whether the virus is associated with asymptomatic cases or with undetected gastroenteritis or respiratory illness is unknown. Further studies are needed to investigate on the occurrence and persistence of SAFV in water environments and its waterborne transmission potential.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Infecciones del Sistema Respiratorio
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Aguas del Alcantarillado
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Infecciones por Cardiovirus
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Cardiovirus
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Enfermedades Gastrointestinales
Tipo de estudio:
Prevalence_studies
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Risk_factors_studies
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Screening_studies
Límite:
Humans
País como asunto:
Europa
Idioma:
En
Año:
2020
Tipo del documento:
Article