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Gamabufotalin induces a negative feedback loop connecting ATP1A3 expression and the AQP4 pathway to promote temozolomide sensitivity in glioblastoma cells by targeting the amino acid Thr794.
Lan, Yu-Long; Chen, Cheng; Wang, Xun; Lou, Jia-Cheng; Xing, Jin-Shan; Zou, Shuang; Hu, Ji-Liang; Lyu, Wen; Zhang, Bo.
  • Lan YL; Department of Neurosurgery, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, First Affiliated Hospital of Southern, University of Science and Technology, Shenzhen, China.
  • Chen C; Department of Neurosurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Wang X; Department of Physiology, Dalian Medical University, Dalian, China.
  • Lou JC; Department of Neurosurgery, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, First Affiliated Hospital of Southern, University of Science and Technology, Shenzhen, China.
  • Xing JS; Department of Neurosurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Zou S; Department of Neurosurgery, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, First Affiliated Hospital of Southern, University of Science and Technology, Shenzhen, China.
  • Hu JL; Department of Neurosurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Lyu W; Department of Neurosurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
  • Zhang B; Department of Physiology, Dalian Medical University, Dalian, China.
Cell Prolif ; 53(1): e12732, 2020 Jan.
Article en En | MEDLINE | ID: mdl-31746080
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bufanólidos / Regulación Enzimológica de la Expresión Génica / Regulación Neoplásica de la Expresión Génica / ATPasa Intercambiadora de Sodio-Potasio / Glioblastoma / Resistencia a Antineoplásicos / Acuaporina 4 / Temozolomida / Proteínas de Neoplasias Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Bufanólidos / Regulación Enzimológica de la Expresión Génica / Regulación Neoplásica de la Expresión Génica / ATPasa Intercambiadora de Sodio-Potasio / Glioblastoma / Resistencia a Antineoplásicos / Acuaporina 4 / Temozolomida / Proteínas de Neoplasias Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article