A CMOS NMR needle for probing brain physiology with high spatial and temporal resolution.
Nat Methods
; 17(1): 64-67, 2020 01.
Article
en En
| MEDLINE
| ID: mdl-31768059
ABSTRACT
Magnetic resonance imaging and spectroscopy are versatile methods for probing brain physiology, but their intrinsically low sensitivity limits the achievable spatial and temporal resolution. Here, we introduce a monolithically integrated NMR-on-a-chip needle that combines an ultra-sensitive 300 µm NMR coil with a complete NMR transceiver, enabling in vivo measurements of blood oxygenation and flow in nanoliter volumes at a sampling rate of 200 Hz.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Oxígeno
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Encéfalo
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Imagen por Resonancia Magnética
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Interpretación de Imagen Asistida por Computador
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Espectroscopía de Resonancia Magnética
Límite:
Animals
Idioma:
En
Año:
2020
Tipo del documento:
Article