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An in silico-in vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Mishto, Michele; Mansurkhodzhaev, Artem; Ying, Ge; Bitra, Aruna; Cordfunke, Robert A; Henze, Sarah; Paul, Debdas; Sidney, John; Urlaub, Henning; Neefjes, Jacques; Sette, Alessandro; Zajonc, Dirk M; Liepe, Juliane.
  • Mishto M; Centre for Inflammation Biology and Cancer Immunology (CIBCI) & Peter Gorer Department of Immunobiology, King's College London, London, United Kingdom.
  • Mansurkhodzhaev A; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Institut für Biochemie, Berlin, Germany.
  • Ying G; Quantitative and Systems Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
  • Bitra A; Division of Immune Regulation, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
  • Cordfunke RA; Division of Immune Regulation, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
  • Henze S; Department of Immunohematology and Bloodbank, Leiden University Medical Center LUMC, Leiden, Netherlands.
  • Paul D; Quantitative and Systems Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
  • Sidney J; Quantitative and Systems Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
  • Urlaub H; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
  • Neefjes J; Bioanalytical Mass Spectrometry Group, Max-Planck-Institute for Biophysical Chemistry, Goettingen, Germany.
  • Sette A; Institut for Clinical Chemistry, University Medical Center Goettingen Bioanalytics, Goettingen, Germany.
  • Zajonc DM; Department of Cell and Chemical Biology, Oncode Institute, Leiden University Medical Center LUMC, Leiden, Netherlands.
  • Liepe J; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, United States.
Front Immunol ; 10: 2572, 2019.
Article en En | MEDLINE | ID: mdl-31803176

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígenos HLA-A / Proteínas Proto-Oncogénicas p21(ras) / Empalme Alternativo / Mapeo Epitopo / Biología Computacional / Epítopos / Neoplasias Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antígenos HLA-A / Proteínas Proto-Oncogénicas p21(ras) / Empalme Alternativo / Mapeo Epitopo / Biología Computacional / Epítopos / Neoplasias Límite: Humans Idioma: En Año: 2019 Tipo del documento: Article