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Triple blockade of EGFR, MEK and PD-L1 has antitumor activity in colorectal cancer models with constitutive activation of MAPK signaling and PD-L1 overexpression.
Napolitano, S; Matrone, N; Muddassir, A L; Martini, G; Sorokin, A; De Falco, V; Giunta, E F; Ciardiello, D; Martinelli, E; Belli, V; Furia, M; Kopetz, S; Morgillo, F; Ciardiello, F; Troiani, T.
  • Napolitano S; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Matrone N; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicin0065, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
  • Muddassir AL; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Martini G; Medical University of Vienna, Institute for Cancer Research, Borschkegasse 8A, 1090, Wien, Austria.
  • Sorokin A; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicin0065, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
  • De Falco V; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Giunta EF; Vall D'Hebron Institute of Oncology (VHIO), Gastrointestinal and neuroendocrine tumor group, C/Natzaret 115-117, 08035, Barcelona, Spain.
  • Ciardiello D; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicin0065, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
  • Martinelli E; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Belli V; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Furia M; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Kopetz S; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Morgillo F; Medical Oncology Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80100, Naples, Italy.
  • Ciardiello F; Department of Biology, University of Naples Federico II, 80126, Naples, Italy.
  • Troiani T; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicin0065, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA.
J Exp Clin Cancer Res ; 38(1): 492, 2019 Dec 16.
Article en En | MEDLINE | ID: mdl-31842958
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Neoplasias Colorrectales / Resistencia a Antineoplásicos / Difenilamina / Clorhidrato de Erlotinib / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Año: 2019 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Neoplasias Colorrectales / Resistencia a Antineoplásicos / Difenilamina / Clorhidrato de Erlotinib / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Año: 2019 Tipo del documento: Article