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The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.
Kowalsky, Allison Ho; Namkoong, Sim; Mettetal, Eric; Park, Hwan-Woo; Kazyken, Dubek; Fingar, Diane C; Lee, Jun Hee.
  • Kowalsky AH; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan 48109.
  • Namkoong S; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan 48109; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon 24341, Republic of Korea.
  • Mettetal E; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan 48109.
  • Park HW; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan 48109; Department of Cell Biology, Myunggok Medical Research Institute, Konyang University College of Medicine, Daejeon 35365, Republic of Korea.
  • Kazyken D; Department of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan 48109.
  • Fingar DC; Department of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan 48109.
  • Lee JH; Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan 48109. Electronic address: leeju@umich.edu.
J Biol Chem ; 295(7): 1769-1780, 2020 02 14.
Article en En | MEDLINE | ID: mdl-31915252
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Peroxidasas / Proteínas / Proteínas Proto-Oncogénicas c-akt / Diana Mecanicista del Complejo 2 de la Rapamicina / Obesidad Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Peroxidasas / Proteínas / Proteínas Proto-Oncogénicas c-akt / Diana Mecanicista del Complejo 2 de la Rapamicina / Obesidad Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article