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An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological Toxicity.
Yeung, Yik Andy; Krishnamoorthy, Veena; Dettling, Danielle; Sommer, Cesar; Poulsen, Kris; Ni, Irene; Pham, Amber; Chen, Wei; Liao-Chan, Sindy; Lindquist, Kevin; Chin, S Michael; Chunyk, Allison Given; Hu, Wenyue; Sasu, Barbra; Chaparro-Riggers, Javier; Djuretic, Ivana.
  • Yeung YA; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA. Electronic address: yeungyik@yahoo.com.
  • Krishnamoorthy V; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Dettling D; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Sommer C; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Poulsen K; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Ni I; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Pham A; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Chen W; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Liao-Chan S; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Lindquist K; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Chin SM; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Chunyk AG; Biomedicine Design, Pfizer Inc., San Diego, CA 94080, USA.
  • Hu W; Drug Safety R&D, Pfizer Inc., San Diego, CA 94080, USA.
  • Sasu B; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA.
  • Chaparro-Riggers J; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA. Electronic address: javier.chaparro-riggers@pfizer.com.
  • Djuretic I; Cancer Immunology Discovery, Oncology R&D, Pfizer Inc., South San Francisco, CA 94080, USA. Electronic address: ivanadj@hotmail.com.
Mol Ther ; 28(3): 889-900, 2020 03 04.
Article en En | MEDLINE | ID: mdl-31981494
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Complejo CD3 / Anticuerpos Biespecíficos / Tirosina Quinasa 3 Similar a fms / Antineoplásicos Inmunológicos / Hematopoyesis Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Complejo CD3 / Anticuerpos Biespecíficos / Tirosina Quinasa 3 Similar a fms / Antineoplásicos Inmunológicos / Hematopoyesis Límite: Animals / Humans Idioma: En Año: 2020 Tipo del documento: Article