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DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
Arloth, Janine; Eraslan, Gökcen; Andlauer, Till F M; Martins, Jade; Iurato, Stella; Kühnel, Brigitte; Waldenberger, Melanie; Frank, Josef; Gold, Ralf; Hemmer, Bernhard; Luessi, Felix; Nischwitz, Sandra; Paul, Friedemann; Wiendl, Heinz; Gieger, Christian; Heilmann-Heimbach, Stefanie; Kacprowski, Tim; Laudes, Matthias; Meitinger, Thomas; Peters, Annette; Rawal, Rajesh; Strauch, Konstantin; Lucae, Susanne; Müller-Myhsok, Bertram; Rietschel, Marcella; Theis, Fabian J; Binder, Elisabeth B; Mueller, Nikola S.
  • Arloth J; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Eraslan G; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Andlauer TFM; Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Martins J; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Iurato S; Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
  • Kühnel B; German Competence Network Multiple Sclerosis (KKNMS), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Waldenberger M; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Frank J; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Gold R; Research Unit of Molecular Epidemiology and Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Hemmer B; Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Luessi F; Research Unit of Molecular Epidemiology and Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Nischwitz S; Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
  • Paul F; German Centre for Cardiovascular Research (DZHK), Berlin, Germany.
  • Wiendl H; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Gieger C; German Competence Network Multiple Sclerosis (KKNMS), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Heilmann-Heimbach S; Department of Neurology, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.
  • Kacprowski T; Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
  • Laudes M; German Competence Network Multiple Sclerosis (KKNMS), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Meitinger T; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Peters A; German Competence Network Multiple Sclerosis (KKNMS), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Rawal R; Department of Neurology, University Medicine Mainz, Johannes Gutenberg University Mainz, Mainz, Germany.
  • Strauch K; Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.
  • Lucae S; German Competence Network Multiple Sclerosis (KKNMS), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Müller-Myhsok B; German Competence Network Multiple Sclerosis (KKNMS), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Rietschel M; NeuroCure Clinical Research Center, Department of Neurology, and Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine, and CharitÏ© -Universitätsmedizin Berlin, Berlin, Germany.
  • Theis FJ; German Competence Network Multiple Sclerosis (KKNMS), Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
  • Binder EB; Department of Neurology with Institute of Translational Neurology, University of Münster, Münster, Germany.
  • Mueller NS; Research Unit of Molecular Epidemiology and Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
PLoS Comput Biol ; 16(2): e1007616, 2020 02.
Article en En | MEDLINE | ID: mdl-32012148
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Análisis Multivariante / Estudios de Asociación Genética / Aprendizaje Profundo Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Análisis Multivariante / Estudios de Asociación Genética / Aprendizaje Profundo Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article