Multiple Input Sensing and Signal Integration Using a Split Cas12a System.

Kempton, Hannah R; Goudy, Laine E; Love, Kasey S; Qi, Lei S

Kempton, Hannah R; Goudy, Laine E; Love, Kasey S; Qi, Lei S.

Kempton HR; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Goudy LE; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Love KS; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Qi LS; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; Department of Chemical and Systems Biology, Stanford University, Stanford, CA 94305, USA; ChEM-H, Stanford University, Stanford, CA 94305, USA. Electronic address: stanley.qi@stanford.edu.

Mol Cell ; 78(1): 184-191.e3, 2020 04 02.

Article en En | MEDLINE | ID: mdl-32027839

Asunto(s)

Proteínas Asociadas a CRISPR; Sistemas CRISPR-Cas; Ingeniería Celular; Neoplasias de la Mama/genética; Neoplasias de la Mama/terapia; Línea Celular Tumoral; Dimerización; Femenino; Células HEK293; Humanos; Activación Transcripcional

Palabras clave

AND gates; Boolean logic; CRISPR-Cas; Cpf1; cell engineering; genetic circuits; immunotherapy; logic gates; split Cas12a; synthetic biology

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ingeniería Celular / Proteínas Asociadas a CRISPR / Sistemas CRISPR-Cas Límite: Female / Humans Idioma: En Año: 2020 Tipo del documento: Article

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