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Synthesis, biological evaluation and molecular modeling study of 2-amino-3,5-disubstituted-pyrazines as Aurora kinases inhibitors.
Bo, Yong-Xin; Xiang, Rong; Xu, Yu; Hao, Shu-Yi; Wang, Xing-Rong; Chen, Shi-Wu.
  • Bo YX; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Xiang R; Department of Medicinal, The Second Clinical Medical College of Northwest Minzu University & The Second Provincial People's Hospital of Gansu Province, Lanzhou 730000, PR China.
  • Xu Y; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Hao SY; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Wang XR; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China.
  • Chen SW; School of Pharmacy, Lanzhou University, Lanzhou 730000, PR China. Electronic address: chenshw@lzu.edu.cn.
Bioorg Med Chem ; 28(5): 115351, 2020 03 01.
Article en En | MEDLINE | ID: mdl-32035750
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Inhibidores de Proteínas Quinasas / Aurora Quinasa A / Aurora Quinasa B / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Inhibidores de Proteínas Quinasas / Aurora Quinasa A / Aurora Quinasa B / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article