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Human PLD structures enable drug design and characterization of isoenzyme selectivity.
Metrick, Claire M; Peterson, Emily A; Santoro, Joseph C; Enyedy, Istvan J; Murugan, Paramasivam; Chen, TeYu; Michelsen, Klaus; Cullivan, Michael; Spilker, Kerri A; Kumar, P Rajesh; May-Dracka, Tricia L; Chodaparambil, Jayanth V.
  • Metrick CM; Physical Biochemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Peterson EA; Biogen Postdoctoral Scientist Program, Biogen, Cambridge, MA, USA.
  • Santoro JC; Medicinal Chemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Enyedy IJ; Bioassays and High Throughput Screens, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Murugan P; Medicinal Chemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Chen T; Bioassays and High Throughput Screens, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Michelsen K; Medicinal Chemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Cullivan M; Physical Biochemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Spilker KA; Physical Biochemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Kumar PR; Physical Biochemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • May-Dracka TL; Physical Biochemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
  • Chodaparambil JV; Medicinal Chemistry, Biotherapeutic and Medicinal Sciences, Biogen, Cambridge, MA, USA.
Nat Chem Biol ; 16(4): 391-399, 2020 04.
Article en En | MEDLINE | ID: mdl-32042197
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfolipasa D Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfolipasa D Límite: Humans Idioma: En Año: 2020 Tipo del documento: Article