Genomic evidence of yellow fever virus in Aedes scapularis, southeastern Brazil, 2016.
Acta Trop
; 205: 105390, 2020 May.
Article
en En
| MEDLINE
| ID: mdl-32044285
ABSTRACT
The southeastern region of Brazil has recently experienced the largest yellow fever disease outbreak in decades. Since July 2016 epizootic events were reported in São Paulo state's north region, where 787 Culicidae were captured as part of public health surveillance efforts and tested using real-time quantitative PCR. One Aedes scapularis pool collected in November 2016 in an agriculture area in Urupês city tested positive for YFV-RNA. Using a validated multiplex PCR approach we were able to recover a complete virus genome sequence from this pool. Phylogenetic analysis of the novel strain and publicly available data indicates that the belongs to the South American genotype 1 clade circulating in Sao Paulo state and is basal to the recent outbreak clade in southeast Brazil. Our findings highlight the need of additional studies, including vector competence studies, to disentangle the role of Aedes scapularis in yellow fever transmission in the Americas.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Fiebre Amarilla
/
Virus de la Fiebre Amarilla
/
Aedes
/
Mosquitos Vectores
Límite:
Animals
/
Humans
País como asunto:
America do sul
/
Brasil
Idioma:
En
Año:
2020
Tipo del documento:
Article